As per the “ Cell reports” study, A new bioengineering process was used by the scientist that develop self-condensation cell culture. This method helps medical science to develop human organ tissue from own human cells for regenerative therapy. This conclusion was made by the researchers at Cincinnati Children's Hospital Medical Center in the U.S. and Yokohama City University (YCU) in Japan.
This technique may be used as primary method to treat type 1 diabetes among 79,000 diagnoses in a year was said by Takanori Takebe, MD - physician-scientist at the Cincinnati Children's Center for Stem Cell and Organoid Medicine.
This is a non-curable disease , so many therapeutics have to been developed to help out the children and adults in the world.
The technique which scientist used are combining donated human organ cells (pancreas, heart, brain, etc.), with mouse organ cells and with induced pluripotent stem cells (iPS). This Pluripotent stem cells act like embryonic cells and form tissues in the body.
The tested results from donated human organ cells (pancreas, heart, brain ) with donated mice cells along with pluripotent stem cells (iPS). This Pluripotent stem cells which are reprogrammed act like embryonic cells and form tissue in the body.
This process uses two types of embryonic stage progenitor cells, they are esenchymal stem cells (MSNs) and human umbilical vascular endothelial cells (HUVECs)
As we know that human pancreatic cells can be transplanted for diabetic patient, but the engraftment success rate is low due to blood supply and Vascularization. This one of the draw back for the researchers for the development of this technique.
For more details:https://epigenetics.geneticconferences.com/
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